STEP TEST
A complete Endometrium Analysis
Implantation is a multi-factorial process and endometrium is its rate limiting factor. A complete
endometrium profile can delineate the causes of implantation failure. The STEP test defines the
role of endometrial factors responsible of infertility, recurrent implantation failure (RIF), recurrent pregnancy loss (RPL) and IVF failure. The STEP test assess multiple endometrial factors at a time that results in complete endometrial analysis.
For a proper implantation, the endometrium needs to be fully developed and mature, functionally receptive, infection-free, immune-balanced and immune-tolerant. STEP test
is the only single test of its kind that gives the complete picture of the endometrium and
explains the unexplained causes of infertility.
What is STEP?
A mother’s endometrial profile is inescapable factor in order to have a successful pregnancy
due to its key role in implantation of embryo and providing nutrition during development.
There are multiple factors which influence the pre-pregnancy stage of Mother. Primary Infertility, RPL and IVF failure are obstacles of healthy pregnancy. Mother need intense care and
cure before she conceives.
Soil Test Endometrium Profile (STEP) defines the role of these influencing factors in infertility,
recurrent pregnancy loss (RPL) , IVF failure or Implantation failure (RIF).
STEP Test will explain following condition of the endometrium
- 1. Endometrial Receptivity
- 2. Endometrial Growth and Maturation
- 3. Maternal immune tolerance
- 4. Endometrial Cytokines imbalance
- 5. Endometrial Inflammation & Infection ( Chronic Endometritis)
* Additional Genital TB can be screen as per the physician requirement
ANALYSIS OF ENDOMETRIUM THROUGH STEP TEST IN UNEXPLAINED INFERTILITY / RIF
Why STEP?
STEP test is specially designed for the need of infertile females who have unexplained infertility and want to know the root cause of their RPL and RIF. STEP test is a combination of multiple markers that thoroughly assess your endometrium for its functional capacity. For proper implantation, the endometrium needs to be fully developed & mature, functionally receptive, infection-free, immune – balanced and immune-tolerant. All these pieces of information about your endometrium are furnished in the single STEP test. STEP test is the only single multimarker test of its kind that gives the complete picture of the endometrium and explains the unexplained causes of infertility.
Advantages
STEP test has several advantages, such as:
- The complete endometrial function and receptivity analysis
- Multi-marker diagnostics instead of single marker
- The test gives patient specific tailored diagnosis & personalized treatment option
The unknown causes are not unknown anymore!
- Unexplained Infertility
- IVF Failure or RIF/RPL
- Endometritis & Infection
- Endometrial Receptivity & Function
- Maternal Immune Tolerance
- Cytokine Imbalance
Who should take STEP Test?
- Women with infertility
- Women with IUI Failure
- Women with IVF Failure
- Women with Recurrent Implantation Failure (RIF)
- Women with recurrent pregnancy loss
Sample Requirement
Endometrial biopsy day: Cycle Day 21-23 [Preferred 21st day]
1. Natural Cycle : 7-9 days after ovulation [LH +7 to LH+9]
2. Mock Cycle: 6-8 days after start of progesterone [P+6 to P+8]
1. Natural Cycle : 7-9 days after ovulation [LH +7 to LH+9]
2. Mock Cycle: 6-8 days after start of progesterone [P+6 to P+8]
